Obviously, you call a shot on a hands or feet for reasons other than causing the most damage as possible, and obviously, you call a shot on the head or on vitals to do lots of damage.
Rather than doing the X1 1/2 or x2 damage for called shots. Use the following rules.
Any shot that does less than x1 damage, must reroll all 5s and 6s on damage (keep the second roll).
Any shot that does x1 1/2 Body, may reroll all 1s, instead.
Any shot that does x2 Body, may reroll all 1s and 2s, instead.
In Frankenstein Crisis random hit locations are not used. Damage is damage. These rules really only work when shots are called.